Biology Program

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Graduate Course Descriptions

This is a list of graduate courses for the MS in Biotechnology and Bioinformatics program offered at CSU Channel Islands.

MGT 471 MGT 421 PHYS 445 BINF 500 BINF 501
BIOL 490 BIOL 502 BIOL 503 BIOL 504 BIOL 505
BIOL 506 BIOL 507 BIOL 508 BIOL 509 BIOL 510
BINF 510 BINF 511 BINF 512 BINF 513 BINF 514
BIOL 600 BIOL 601

Common Core Courses (16 units)

MGT 471 PROJECT MANAGEMENT (3)
Three hours lectures per week
Presents the principles of project management, which is a special form of work organization, that focuses on a one-time objective. Discusses all aspects of project management: definition of objectives, selection of team and other resources, establishing of timing and sequences, creation of monitoring and control processes, and development of analysis and reporting mechanisms. Course Learning Objectives

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BINF 500 DNA AND PROTEIN SEQUENCE ANALYSIS (3)
Three hours lecture per week
Prerequisite: BIOL 400 or consent of instructor
This course will introduce the computational aspects of biological inference from nucleic acid and protein sequences. Pairwise sequence comparison and multiple sequence alignment will be studied in detail. Additional topics include: RNA structure prediction, conserved sequence pattern recognition (sequence profile analysis), phylogenetic analysis algorithms, sequence data as a means to study molecular evolution, models and algorithms for genetic regulation, contig assembly, PAM and BLOSUM matrices, protein three dimensional structure prediction. Course Learning Objectives

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BIOL 502 TECHNIQUES IN GENOMICS/PROTEOMICS (2)
Six hours laboratory per week
Prerequisite: BIOL 401 or consent of the instructor
This laboratory course introduces students to the current techniques and methodologies in the fields of comparative and functional genomics and proteomics. Topics and techniques covered include genome sequencing, microarrays, mutagenesis, transgenic plants and animals, single nucleotide polymorphism (SNP) discovery and analysis. Students will gain hands-on lab bench experience and will make on-site visits to high volume regional biotechnology facilities. Course Learning Objectives

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BIOL 503 BIOTECHNOLOGY LAW AND REGULATION (3)
Three hours lecture per week
Individual and organizational responsibility in R&D and commercial aspects of biotechnology. Topics include: intellectual property, privacy, government and industrial regulation, liability, ethics, and policy responses to societal concerns in the U.S. and abroad. Case studies involving gene therapy, cloning, and biomaterials in the medical and health sector, and farming and crop modification in the agricultural sector will be explored in detail. Course Learning Objectives

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BIOL 600 TEAM PROJECT (4)
Prerequisite: Program approval
In this course, students will work individually and in teams to analyze, research, discuss and report on subjects relevant to the biotechnology industry. Course Learning Objectives

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BIOL 601 SEMINAR IN BIOTECHNOLOGY AND BIOINFORMATICS (1)
Discussion of up-to-date research and development findings with guest speakers, visiting scientists and industry professionals. Course Learning Objectives

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Graduate Courses in Biotechnology (17 units)

Required Courses (7 units)

BIOL 504 MOLECULAR CELL BIOLOGY (3)
Three hours lecture per week
Prerequisite: BIOL 300 or consent of instructor
This course will examine molecular and mechanistic aspects of cell biology. Topics include: cell biochemistry and biosynthesis, cell signaling, regulation of the cell cycle and membrane trafficking. Course Learning Objectives

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BIOL 505 MOLECULAR STRUCTURE (4)
Three hours lecture and three hours laboratory per week
Prerequisite: BIOL 400 or consent of instructor
This course will examine the structural biology of proteins. Topics include general principles of protein structure, the biochemical function of proteins, the relationship of protein structure to its function and experimental approaches to determining and predicting protein structure and function. Course Learning Objectives

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Electives (10 units)

A minimum of 10 units chosen from the following courses and/or from the elective courses under the Bioinformatics Emphasis:

BIOL 490 SPECIAL TOPICS: Bioprocess Engineering (3)
Three hours seminar per week

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BIOL 506 MOLECULAR EVOLUTION (4)
Three hours lecture and three hours laboratory per week
Prerequisite: BIOL 400 or BIOL 401 or consent of instructor
This course will examine evolutionary change at the molecular level. Topics include: The driving forces behind the evolutionary process, the effects of the various molecular mechanisms on the structure of genes, proteins, and genomes, the methodology for dealing with molecular data from an evolutionary perspective and the logic of molecular hypothesis testing. Course Learning Objectives

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BIOL 507 PHARMACOGENOMICS AND PHARMACOPROTEOMICS (3)
Three hours lecture per week
Prerequisite: BINF 500, BIOL 504 or permission of instructor
Structural and functional genomics with an emphasis on how these fields operate in drug discovery and optimization. Topics include: genetics of the human response to prophylactic and therapeutic agent, impact of genetic variation on therapeutic efficacy, disease mechanisms, proteomics of genetic and communicable disease, drug action and toxicity, structure encoding, lead discovery and optimization, parallel synthesis, screening virtual libraries. Course Learning Objectives

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BIOL 508 ADVANCED IMMUNOLOGY (4)
Three hours lecture and three hours laboratory per week
Prerequisite: BIOL 300 or consent of instructor
This course will examine cellular and molecular aspects of the immune system. Topics include: molecular genetics and molecular structure of immunoglobulin, T cell receptor, and the MHC antigens; the functions and dysfunctions of the components of the immune system; applications of immunological technologies in modern scientific research and development. Course Learning Objectives

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BIOL 509 PLANT BIOTECHNOLOGY (4)
Three hours lecture and three hours laboratory per week
Prerequisite: BIOL 400 and BIOL 422 or consent of instructor
This course will examine the scientific and technical advances which underlie the production of genetically modified crops. Topics include: plant genome organization and gene expression, plant tissue culture and genetic transformation, genetic manipulation to confer resistance to herbicides, pests and disease and strategies for engineering stress tolerance and the improvement of crop yield and quality. Course Learning Objectives

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BIOL 510 TISSUE CULTURE TECHNIQUES AND STEM CELL TECHNOLOGY (3)
One hours lecture per week and six hours laboratory per week
Prerequisite: BIOL 300 or consent of instructor
Examines theory and concepts of animal and plant cell and tissue culturing. Focuses on stem cell technology including types of stem cells, ethics of stem cells, pluripotency, culture methods, characterization, monitoring tools such as imaging and differentiation strategies. Course Learning Objectives

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MGT 421 HUMAN RESOURCE MANAGEMENT (3)
Three hours lecture per week
Examines principles, methods and procedures in the management of human resources. Topics include developing planning objectives for HR management, legal compliance, job analysis, recruiting, selection, training, compensation and employee relations. Course Learning Objectives

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Graduate Courses in Bioinformatics (18 units)

Required Courses (12 units)

BINF 501 BIOLOGICAL INFORMATICS (3)
Three hours lecture per week
Prerequisite: BIOL 431 or consent of instructor
This course describes relational data models and database management systems with an emphasis on answering biologically important questions; teaches the theories and techniques of constructing relational databases to store various biological data, including sequences, structures, genetic linkages and maps, and signal pathways. Topics include: relational database query language SQL and the ORACLE database management system, summary of currently existing biological databases, web based programming tools, data integration and security, future directions for biological database development. Course Learning Objectives

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BINF 510 DATABASE SYSTEMS FOR BIOINFORMATICS (3)
Three hours lecture per week
Prerequisite: BINF 501, COMP 420, or consent of instructor
This course is an applied, hands-on sequel to BINF 501, designed for students with interests in careers as professional programmers, analysts, designers, and managers involved in design or implementation of large bioinformatic systems. Covers concepts and methods for the design, creation, query and management of large enterprise databases, functions and characteristics of the leading database management systems. Topics include: object oriented database systems, distributed database systems, advanced database management topics, web application design and development, data warehouse systems, database mining. Course Learning Objectives

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BINF 511 COMPUTATIONAL GENOMICS (3)
Three hours lecture per week
Prerequisite: BINF 500 or consent of instructor
This course applies the theories and algorithms taught in BINF 500 to real-life genomic data sets, with an emphasis on practical applications, hands-on analysis, integrated approaches and collaboration. Lecture and laboratory will explore the computational and engineering tools for analyzing genomic data. The relationships between sequence, structure, and function in complex biological networks will be studied using quantitative modeling. Course Learning Objectives

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BINF 513 PROGRAMMING FOR BIOINFORMATICS (3)
Three hours lecture per week
Prerequisite: BINF 501 and COMP 462 or equivalent, or permission of instructor
This course will provide theory and practical training in the development of programming tools and data processing systems for use in genomic/sequence analysis. There will be a strong emphasis on the development of fully-functional web-based applications under the client/server model. Students will be required to complete a term project which will involve the development of a complete client/server application directed toward a relevant bioinformatics task. Course Learning Objectives

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Electives (6 units)

A minimum of two courses chosen from the following and/or from the elective courses under the Biotechnology Emphasis, with at least one course in the BINF category:

BINF 512 ALGORITHMS FOR BIOINFORMATICS (3)
Three hours lecture per week
Prerequisite: BINF 500 or consent of instructor
This course will cover advanced theory in the area of biological informatics and will build on concepts introduced in BINF 500. Topics include: methods to support construction and application of combinatorial biochemical libraries, applications of algorithmic information theory, string matching, dynamic programming, prediction of three-dimensional protein structure from peptide sequence. Course Learning Objectives

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BINF 514 STATISTICAL METHODS IN COMPUTATIONAL BIOLOGY (3)
Three hours lecture per week
Prerequisite: BIOL 202, MATH 151 or consent of instructor
Techniques in statistical inference and stochastic modeling required for the interpretation and utilization of genomic data, including biological sequence alignment and analysis, sequence structure and function prediction, database searching, gene expression profiling, statistical genetics, phylogenetic inference and genetic epidemiology. Course Learning Objectives

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PHYS 445 IMAGE ANALYSIS & PATTERN RECOGNITION (3)
Three hours of lecture in the lab per week.
Prerequisite: PHYS/COMP/MATH 345 or consent of instructor.
The course addressses the issue of analyzing the pattern content within an image. Pattern recognition of image segmentation, feature extraction and classification. The principles and concepts underpinning pattern recognition, and the evolution, utility and limitations of various techniques (including neural networks) will be studied. Programming exercises will be used to implement examples and applications of pattern recognition processes, and their performance on a variety of diverse synthetic and real images will be studied, and an individual project report will be completed. Course Learning Objectives

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MGT 421 HUMAN RESOURCE MANAGEMENT (3)
Three hours per week
Examines principles, methods and procedures in the management of human resources. Topics include developing planning objectives for HR management, legal compliance, job analysis, recruiting, selection, training, compensation and employee relations. Course Learning Objectives

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